DNA Binding Site

Accessions: ECK120011208 (RegulonDB 7.5)
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length: 40
Sequence: cttagatcaaTTTTTGCAATCATTAGCAAAaagattaata
Binding TFs: ECK120004959 (Bacterial regulatory helix-turn-helix protein, lysR family, LysR substrate binding domain)
Binding Motifs: ArgP mwkwTTrTsdmwKrthdm
Publications: Bouvier J., Stragier P., Morales V., Remy E., Gutierrez C. Lysine represses transcription of the Escherichia coli dapB gene by preventing its activation by the ArgP activator. J Bacteriol. 190(15):5224-9 (2008). [Pubmed]

Laishram RS., Gowrishankar J. Environmental regulation operating at the promoter clearance step of bacterial transcription. Genes Dev. 21(10):1258-72 (2007). [Pubmed]

Marbaniang CN., Gowrishankar J. Role of ArgP (IciA) in Lysine-Mediated Repression in Escherichia coli. J Bacteriol. 193(21):5985-96 (2011). [Pubmed]

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