DNA Binding Site

Accessions: 1ahd_A (3D-footprint 20231221), 4xid_B (3D-footprint 20231221), 9ant_E (3D-footprint 20231221)
Organisms: Drosophila melanogaster, Drosophila subobscura
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Sequence: GAAAGCCATTAGAG
Type: Heterodimer
Binding TFs: 1ahd_P (Homeobox domain)
9ant_B (Homeobox domain)
4xid_A (Homeobox domain)
Binding Motifs: 1ahd_P AnnnCATtAGA
4xid_A CcaTTAG
9ant_B CTAATAG
Publications: Billeter M., Qian Y.-Q., Otting G., Mulller M., Gehring W. J., Wutethrich K. Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J. Mol. Biol. 234:1084-1093 (1993). [Pubmed]

Zandarashvili L, Nguyen D, Anderson KM, White MA, Gorenstein DG, Iwahara J. Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys J 109:1026-37 (2015). [Pubmed]

Fraenkel E, Pabo C.O. Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nature structural biology 5:692-7 (1998). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.