DNA Binding Site

Accessions: 1akh_C (3D-footprint 20231221), 1le8_C (3D-footprint 20231221)
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 19
Sequence: CATGTAAAAATTTACATCA
Type: Heterodimer
Binding TFs: 1akh_A (Homeobox domain, Homeobox KN domain)
1akh_B (Homeobox domain, Homeobox KN domain)
1le8_A (Homeobox domain, Homeobox KN domain)
1le8_B (Homeobox domain, Homeobox KN domain)
Binding Motifs: 1akh_A TnTnTCA
1akh_AB TGAnAnAnnnTTTTACA
1le8_A TTACnTCA
1le8_AB GnAnnannTTACATCA
1le8_B GTAnnr
Publications: Li T, Jin Y, Vershon A.K, Wolberger C. Crystal structure of the MATa1/MATalpha2 homeodomain heterodimer in complex with DNA containing an A-tract. Nucleic acids research 26:5707-18 (1998). [Pubmed]

Ke A, Mathias J.R, Vershon A.K, Wolberger C. Structural and thermodynamic characterization of the DNA binding properties of a triple alanine mutant of MATalpha2. Structure (London, England : 1993) 10:961-71 (2002). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.