DNA Binding Site

Accessions: AAACAAAG (UniPROBE 20160601), MA0869.3.15 (JASPAR 2024), MA0869.3.4 (JASPAR 2024)
Organisms: Mus musculus, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: AAACAAAG
Type: Heterodimer
Binding TFs: Q7M6Y2 (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00030A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00062A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00069A (HMG (high mobility group) box, Domain of unknown function (DUF1898), SOX transcription factor)
UP00075A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
UP00401A (HMG (high mobility group) box, Domain of unknown function (DUF1898))
Q7M6Y2
Binding Motifs: UP00069A_7 khtaATTATAATwwdm
UP00069A_11 mwaAACAATTrAwhw
UP00030A_1 / UP00069A_1 wkwarAACAAWGraywa
UP00062A_1 akdarAACAAAGracww
UP00069A_13 twyhATTGTTbtmamw
UP00069A_15 wwtyaATTcAwTamdk
UP00069A_9 / UP00075A_1 wrkwgAACAATwrrtwt
UP00069A_5 wtwrgAACAATwwwtw
UP00069A_3 twATTGTTcthawh
UP00401A_1 tadAACAAwGrvrw
UP00069A_8 ykyasACAATrgmks
UP00069A_12 gwycacATTCAtryrat
UP00030A_2 / UP00069A_2 arAATTGTywkrrw
UP00062A_2 grwarAATTGTtasrra
UP00069A_14 gkrsyraATtyrwdhm
UP00069A_10 / UP00075A_2 btramTGwmATtysr
UP00069A_16 myaTaATTGTTakys
UP00069A_4 mmwyasACAAAGrawt
UP00069A_6 rtrytGGgtGGGwawwt
MA0869.3 GAACAAAG
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

Harley VR, Clarkson MJ, Argentaro A. The molecular action and regulation of the testis-determining factors, SRY (sex-determining region on the Y chromosome) and SOX9 [SRY-related high-mobility group (HMG) box 9]. Endocr Rev 24:466-87 (2003). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.