DNA Binding Site

Accessions: 1qne_F (3D-footprint 20231221), 1vtl_B (3D-footprint 20231221), 1vto_F (3D-footprint 20231221), 6ueq_D (3D-footprint 20231221)
Organisms: Arabidopsis thaliana
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Sequence: TGCCCTTTTATAGC
Type: Heterodimer
Binding TFs: 6ueq_B (Transcription factor TFIID (or TATA-binding protein, TBP))
1qne_B / 1vto_B (Transcription factor TFIID (or TATA-binding protein, TBP))
1vtl_E (Transcription factor TFIID (or TATA-binding protein, TBP))
Binding Motifs: 1vtl_E TATAAaAg
1qne_B cTtTTATA
1vto_B TATAAaAg
6ueq_B CTtTTATa
Publications: Patikoglou G.A, Kim J.L, Sun L, Yang S.H, Kodadek T, Burley S.K. TATA element recognition by the TATA box-binding protein has been conserved throughout evolution. Genes & development 13:3217-30 (1999). [Pubmed]

Kim J.L, Nikolov D.B, Burley S.K. Co-crystal structure of TBP recognizing the minor groove of a TATA element. Nature 365:520-7 (1993). [Pubmed]

Kim J.L, Burley S.K. 1.9 A resolution refined structure of TBP recognizing the minor groove of TATAAAAG. Nature structural biology 1:638-53 (1994). [Pubmed]

Afek A, Shi H, Rangadurai A, Sahay H, Senitzki A, Xhani S, Fang M, Salinas R, Mielko Z, Pufall MA, Poon GMK, Haran TE, Schumacher MA, Al-Hashimi HM, Gordân R. DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature 587:291-296 (2020). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.