DNA Binding Site

Accessions: 3kmp_C (3D-footprint 20231221), 5x6g_C (3D-footprint 20231221)
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Sequence: TCAGTCTAGACATA
Type: Heterodimer
Binding TFs: 3kmp_A (MH1 domain)
3kmp_B (MH1 domain)
5x6g_B (MH1 domain)
5x6g_A (MH1 domain)
Binding Motifs: 3kmp_A TGtCTa
3kmp_AB TGTCTAGaCT
5x6g_A tAGaCA
5x6g_AB TGTCTAGACT
Publications: BabuRajendran N, Palasingam P, Narasimhan K, Sun W, Prabhakar S, Jauch R, Kolatkar P.R. Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors. Nucleic acids research 38:3477-88 (2010). [Pubmed]

Chai N, Li WX, Wang J, Wang ZX, Yang SM, Wu JW. Structural basis for the Smad5 MH1 domain to recognize different DNA sequences. Nucleic Acids Res 43:9051-64 (2015). [Pubmed]

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