DNA Binding Site

Accessions: aprE_2 (DBTBS 1.0)
Names: aprE_2
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 60
Sequence: gatataccTAAATagagaTAAAAtcatctcaaaAAAATgggtctactAAAATattattcc
Binding TFs: DegU (Response regulator receiver domain, Bacterial regulatory proteins, luxR family)
Binding Motifs: DegU_1 wAAAw
DegU_2 TAAwd
Publications: Ferrari E, Howard S.M, Hoch J.A. Effect of stage 0 sporulation mutations on subtilisin expression. Journal of bacteriology 166:173-9 (1986). [Pubmed]

Ogura M, Shimane K, Asai K, Ogasawara N, Tanaka T. Binding of response regulator DegU to the aprE promoter is inhibited by RapG, which is counteracted by extracellular PhrG in Bacillus subtilis. Molecular microbiology 49:1685-97 (2003). [Pubmed]

Kunst F, Pascal M, Lepesant-Kejzlarova J, Lepesant J.A, Billault A, Dedonder R. Pleiotropic mutations affecting sporulation conditions and the syntheses of extracellular enzymes in Bacillus subtilis 168. Biochimie 56:1481-9 (1974). [Pubmed]

Ayusawa D, Yoneda Y, Yamane K, Maruo B. Pleiotropic phenomena in autolytic enzyme(s) content, flagellation, and simultaneous hyperproduction of extracellular alpha-amylase and protease in a Bacillus subtilis mutant. Journal of bacteriology 124:459-69 (1975). [Pubmed]

Yoneda Y, Maruo B. Mutation of Bacillus subtilis causing hyperproduction of alpha-amylase and protease, and its synergistic effect. Journal of bacteriology 124:48-54 (1975). [Pubmed]

Tanaka T, Kawata M. Cloning and characterization of Bacillus subtilis iep, which has positive and negative effects on production of extracellular proteases. Journal of bacteriology 170:3593-600 (1988). [Pubmed]

Mukai K, Kawata-Mukai M, Tanaka T. Stabilization of phosphorylated Bacillus subtilis DegU by DegR. Journal of bacteriology 174:7954-62 (1992). [Pubmed]

Shimane K, Ogura M. Mutational analysis of the helix-turn-helix region of Bacillus subtilis response regulator DegU, and identification of cis-acting sequences for DegU in the aprE and comK promoters. Journal of biochemistry 136:387-97 (2004). [Pubmed]

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