DNA Binding Motif

Accessions: 5uan_AB (3D-footprint 20231221)
Names: Retinoic acid receptor RXR-alpha
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of multi-domain RAR-beta-RXR-alpha heterodimer on DNA
Length: 9
Consensus: GGtCannGG
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 96 0 G
03 16 13 13 54 t
04 0 96 0 0 C
05 54 16 13 13 a
06 24 24 24 24 n
07 24 24 24 24 n
08 0 0 96 0 G
09 0 0 96 0 G
Type: Heterodimer
Binding TFs: 5uan_A (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
5uan_B (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains))
Binding Sites: 5uan_E
5uan_F
Publications: Chandra V, Wu D, Li S, Potluri N, Kim Y, Rastinejad F. The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission. Nat Commun 8:868 (2017). [Pubmed]

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