DNA Binding Motif

Accessions: 3mfk_AB (3D-footprint 20231221)
Names: Protein C-ets-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Ets1 complex with stromelysin-1 promoter DNA
Length: 13
Consensus: AGGAagnnnnTCC
Weblogo:
PSSM: P0 A C G T
01 69 8 8 11 A
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 52 19 17 8 a
06 8 17 61 10 g
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 0 0 0 96 T
12 0 96 0 0 C
13 0 96 0 0 C
Type: Heterodimer
Binding TFs: 3mfk_A (Ets-domain)
3mfk_B (Ets-domain)
Binding Sites: 3mfk_C
3mfk_D
Publications: Babayeva N.D, Wilder P.J, Shiina M, Mino K, Desler M, Ogata K, Rizzino A, Tahirov T.H. Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA. Cell cycle (Georgetown, Tex.) 9:3054-62 (2010). [Pubmed]

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