DNA Binding Motif

Accessions: 6p0s_ABE (3D-footprint 20231221)
Names: DNA-binding protein Fis
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of ternary DNA complex "FX2" containing E. coli Fis and phage lambda Xis
Length: 16
Consensus: GyCtGTTnnnTAnnCA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 3 26 10 57 y
03 3 71 15 7 C
04 9 19 3 65 t
05 0 0 96 0 G
06 0 0 0 96 T
07 10 7 3 76 T
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 7 7 7 75 T
12 92 0 3 1 A
13 24 24 24 24 n
14 24 24 24 24 n
15 0 96 0 0 C
16 96 0 0 0 A
Type: Heterodimer
Binding TFs: 6p0s_A (Bacterial regulatory protein, Fis family)
6p0s_B (Bacterial regulatory protein, Fis family)
Binding Sites: 6p0s_C
6p0s_D
Publications: Hancock SP, Cascio D, Johnson RC. Cooperative DNA binding by proteins through DNA shape complementarity. Nucleic Acids Res 47:8874-8887 (2019). [Pubmed]

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