DNA Binding Motif

Accessions: 5t01_AB (3D-footprint 20231221)
Names: Transcription factor AP-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human c-Jun DNA binding domain homodimer in complex with methylated DNA
Length: 9
Consensus: angAGTCAt
Weblogo:
PSSM: P0 A C G T
01 57 13 13 13 a
02 24 24 24 24 n
03 13 15 48 20 g
04 96 0 0 0 A
05 0 0 96 0 G
06 0 0 0 96 T
07 0 96 0 0 C
08 96 0 0 0 A
09 13 13 13 57 t
Binding TFs: 5t01_A / 5t01_B (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 5t01_C
5t01_D
Publications: Hong S, Wang D, Horton JR, Zhang X, Speck SH, Blumenthal RM, Cheng X. Methyl-dependent and spatial-specific DNA recognition by the orthologous transcription factors human AP-1 and Epstein-Barr virus Zta. Nucleic Acids Res 45:2503-2515 (2017). [Pubmed]

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