DNA Binding Motif

						

			
Accessions: 4ati_AB (3D-footprint 20231221)

			
Names: MICROPHTHALMIA-ASSOCIATED TRANSCRIPTION FACTOR
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: MITF:M-box complex
Length: 9
Consensus: TCATGTGCT
Weblogo: 
PSSM: P0      A      C      G      T
01      0      0      0     96      T
02      0     96      0      0      C
03     67     11      9      9      A
04      0      0      0     96      T
05      9      9     69      9      G
06      0      0      0     96      T
07      0      0     96      0      G
08      9     67     11      9      C
09      0      0      0     96      T
Type: Heterodimer
Binding TFs: 4ati_A (Helix-loop-helix DNA-binding domain)
4ati_B (Helix-loop-helix DNA-binding domain)
Binding Sites: 4ati_C
4ati_D
			
Publications: Pogenberg V, Ogmundsdóttir M.H, Bergsteinsdóttir K, Schepsky A, Phung B, Deineko V, Milewski M, Steingrímsson E, Wilmanns M. Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF. Genes & development 26:2647-58 (2012). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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