footprintDB - a database of transcription factors with annotated cis elements (DNA motifs and sites) and binding interfaces

DNA Binding Motif

Accessions:	CRP (RegulonDB 7.5)
Names:	CRP, CRP transcriptional dual regulator
Organisms:	ECK12
Libraries:	RegulonDB 7.5 ¹ ¹ Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length:	22
Consensus:	wtgtGAwyyasaTCACAwwwtt
Weblogo:
PSSM:	P0 A C G T 01 85 41 29 81 w 02 30 35 18 153 t 03 33 12 139 52 g 04 17 45 19 155 t 05 34 3 176 23 G 06 167 35 19 15 A 07 60 34 49 93 w 08 54 73 46 63 y 09 42 64 46 84 y 10 102 25 52 57 a 11 42 63 79 52 s 12 121 25 47 43 a 13 17 15 10 194 T 14 29 196 8 3 C 15 204 0 17 15 A 16 25 194 9 8 C 17 167 16 35 18 A 18 79 42 19 96 w 19 80 16 1 139 w 20 64 20 16 136 w 21 41 28 13 154 t 22 50 39 52 95 t
Binding TFs:	ECK120004636 (Cyclic nucleotide-binding domain, Bacterial regulatory proteins, crp family, Crp-like helix-turn-helix domain)
Binding Sites:	ECK120011238 ECK120011310 ECK120011316 ECK120011318 ECK120011343 ECK120011443 ECK120011446 ECK120011452 ECK120011480 ECK120011487 ECK120011567 ECK120011754 ECK120011771 ECK120011773 ECK120011784 ECK120011795 ECK120011798 ECK120011800 ECK120011812 ECK120011814 ECK120011862 ECK120011865 ECK120011916 ECK120011945 ECK120011947 ECK120012034 ECK120012046 ECK120012054 ECK120012058 ECK120012085 ECK120012116 ECK120012129 ECK120012137 ECK120012194 ECK120012197 ECK120012200 ECK120012257 ECK120012343 ECK120012345 ECK120012356 ECK120012359 ECK120012374 ECK120012403 ECK120012405 ECK120012438 ECK120012442 ECK120012490 ECK120012508 ECK120012523 ECK120012557 ECK120012567 ECK120012575 ECK120012583 ECK120012600 ECK120012662 ECK120012673 ECK120012702 ECK120012710 ECK120012721 ECK120012736 ECK120012738 ECK120012754 ECK120012776 ECK120012779 ECK120012830 ECK120012882 ECK120012909 ECK120012917 ECK120012949 ECK120012973 ECK120013023 ECK120013025 ECK120013030 ECK120013033 ECK120013036 ECK120013038 ECK120013041 ECK120013043 ECK120013045 ECK120013047 ECK120013051 ECK120013055 ECK120013057 ECK120013059 ECK120013287 ECK120013297 ECK120013331 ECK120013333 ECK120013340 ECK120013365 ECK120013367 ECK120013379 ECK120013388 ECK120013392 ECK120013413 ECK120013423 ECK120013437 ECK120013439 ECK120013442 ECK120013446 ECK120013466 ECK120013468 ECK120013470 ECK120013483 ECK120013489 ECK120013493 ECK120013520 ECK120013523 ECK120013545 ECK120013562 ECK120013565 ECK120013571 ECK120013574 ECK120013580 ECK120013643 ECK120013648 ECK120013651 ECK120013653 ECK120013707 ECK120013709 ECK120013711 ECK120013713 ECK120013715 ECK120013719 ECK120013721 ECK120013723 ECK120013728 ECK120013770 ECK120013797 ECK120013820 ECK120013822 ECK120013834 ECK120013889 ECK120013893 ECK120013944 ECK120013966 ECK120013972 ECK120013974 ECK120013988 ECK120013990 ECK120013996 ECK120014009 ECK120014011 ECK120014013 ECK120014032 ECK120014061 ECK120014110 ECK120014121 ECK120014126 ECK120014148 ECK120014150 ECK120014152 ECK120014163 ECK120015205 ECK120015231 ECK120015562 ECK120015669 ECK120015678 ECK120015684 ECK120015703 ECK120015745 ECK120015761 ECK120015998 ECK120016026 ECK120016028 ECK120016030 ECK120016034 ECK120016038 ECK120016040 ECK120016042 ECK120016044 ECK120016046 ECK120016048 ECK120016050 ECK120016052 ECK120016054 ECK120016149 ECK120016152 ECK120016489 ECK120016534 ECK120016824 ECK120016826 ECK120016828 ECK120016830 ECK120016832 ECK120016834 ECK120016836 ECK120016838 ECK120016840 ECK120016842 ECK120016844 ECK120016846 ECK120016848 ECK120016850 ECK120016852 ECK120016854 ECK120016856 ECK120016858 ECK120016860 ECK120016862 ECK120016864 ECK120016866 ECK120016868 ECK120016887 ECK120018496 ECK120018504 ECK120026335 ECK120026467 ECK120029481 ECK120029537 ECK120029608 ECK120030688 ECK120033077 ECK120033079 ECK120033081 ECK120034575 ECK120034894 ECK120035029 ECK120035048 ECK120048808 ECK120048830 ECK120048932 ECK120051348 ECK120051350 ECK120051352 ECK120051468 ECK125108611 ECK125108617 ECK125108619 ECK125108621 ECK125108648 ECK125110251 ECK125134898 ECK125135087 ECK125135218 ECK125135220 ECK125135222 ECK125135224 ECK125135226 ECK125135229 ECK125135236 ECK125141164 ECK125141209 ECK125141242 ECK125141244 ECK125141260 ECK125141459 ECK125141476 ECK125141477
Publications:	Lange R., Hengge-Aronis R. Identification of a central regulator of stationary-phase gene expression in Escherichia coli. Mol Microbiol. 5(1):49-59 (1991). [Pubmed] McCann MP., Fraley CD., Matin A. The putative sigma factor KatF is regulated posttranscriptionally during carbon starvation. J Bacteriol. 175(7):2143-9 (1993). [Pubmed] Torres B., Porras G., Garcia JL., Diaz E. Regulation of the mhp cluster responsible for 3-(3-hydroxyphenyl) propionic acid degradation in escherichia coli. J Biol Chem. 278(30):27575-85. (2003). [Pubmed] Friden P., Tsui P., Okamoto K., Freundlich M. Interaction of cyclic AMP receptor protein with the ilvB biosynthetic operon in E. coli. Nucleic Acids Res. 12(21):8145-60 (1984). [Pubmed] Lloyd GS., Hollands K., Godfrey RE., Busby SJ. Transcription initiation in the Escherichia coli K-12 malI-malX intergenic region and the role of the cyclic AMP receptor protein. FEMS Microbiol Lett. 288(2):250-7 (2008). [Pubmed] Plumbridge J., Kolb A. CAP and Nag repressor binding to the regulatory regions of the nagE-B and manX genes of Escherichia coli. J Mol Biol. 217(4):661-79 (1991). [Pubmed] Zheng D., Constantinidou C., Hobman JL., Minchin SD. Identification of the CRP regulon using in vitro and in vivo transcriptional profiling. Nucleic Acids Res. 32(19):5874-93 (2004). [Pubmed] Nishino K., Senda Y., Yamaguchi A. CRP regulator modulates multidrug resistance of Escherichia coli by repressing the mdtEF multidrug efflux genes. J Antibiot (Tokyo). 61(3):120-7 (2008). [Pubmed] Hollands K., Lee DJ., Lloyd GS., Busby SJ. Activation of sigma-dependent transcription in Escherichia coli by the cyclic AMP receptor protein requires an unusual promoter organization. Mol Microbiol (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.

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