DNA Binding Motif

Accessions: 5k98_BP (3D-footprint 20210203)
Names: Antitoxin HipB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of HipA-HipB-O2-O3 complex
Length: 18
Consensus: TATCCCnnnnnnGGGATA
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 96 0 0 0 A
03 6 6 6 78 T
04 0 96 0 0 C
05 0 96 0 0 C
06 0 96 0 0 C
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 24 24 24 24 n
13 0 0 96 0 G
14 6 6 78 6 G
15 0 0 96 0 G
16 78 6 6 6 A
17 6 6 6 78 T
18 78 6 6 6 A
Binding TFs: 5k98_P / 5k98_B (Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix domain, Helix-turn-helix, Cro/C1-type HTH DNA-binding domain)
Binding Sites: 5k98_E
5k98_T
Publications: Schumacher MA, Balani P, Min J, Chinnam NB, Hansen S, Vulić M, Lewis K, Brennan RG. HipBA-promoter structures reveal the basis of heritable multidrug tolerance. Nature 524:59-64 (2015). [Pubmed]

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