DNA Binding Motif

Accessions: 1p7h_LN (3D-footprint 20231221)
Names: Nuclear factor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structure of NFAT1 bound as a dimer to the HIV-1 LTR kB element
Length: 13
Consensus: TTCCnAnnnGGGA
Weblogo:
PSSM: P0 A C G T
01 7 7 9 73 T
02 0 0 0 96 T
03 0 96 0 0 C
04 0 96 0 0 C
05 24 24 24 24 n
06 66 7 9 14 A
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 0 0 96 0 G
11 0 0 96 0 G
12 23 0 73 0 G
13 66 14 7 9 A
Binding TFs: 1p7h_L / 1p7h_N (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 1p7h_A
1p7h_B
1p7h_C
1p7h_D
Publications: Giffin M.J, Stroud J.C, Bates D.L, von Koenig K.D, Hardin J, Chen L. Structure of NFAT1 bound as a dimer to the HIV-1 LTR kappa B element. Nature structural biology 10:800-6 (2003). [Pubmed]

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