DNA Binding Motif

Accessions: ONECUT2_DBD (HumanTF 1.0), MA0756.1 (JASPAR 2024)
Names: ONECUT2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 14
Consensus: aaaAAATCrATAww
Weblogo:
PSSM: P0 A C G T
01 1028 445 539 366 a
02 1363 192 515 307 a
03 2378 254 375 507 a
04 2378 157 83 595 A
05 2378 12 114 20 A
06 2378 1 18 6 A
07 8 8 9 2378 T
08 6 2378 0 5 C
09 893 16 1485 0 r
10 2378 2 1 22 A
11 20 14 0 2378 T
12 2378 84 105 205 A
13 1547 576 238 832 w
14 651 526 237 964 w
Type: Heterodimer
Binding TFs: ONECUT2_DBD (Homeobox domain, CUT domain)
O95948 (Homeobox domain, CUT domain)
O95948
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Samadani U., Costa R. H. The transcriptional activator hepatocyte nuclear factor 6 regulates liver gene expression. Mol. Cell. Biol. 16:6273-6284 (1996). [Pubmed]

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