DNA Binding Motif

						

			
Accessions: 1puf_B (3D-footprint 20231221)

			
Names: Pre-B-cell leukemia transcription factor-1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of HoxA9 and Pbx1 homeodomains bound to DNA
Length: 6
Consensus: TaTCAT
Weblogo: 
PSSM: P0      A      C      G      T
01      9      9     11     67      T
02     57     11      9     19      a
03      0      0      0     96      T
04      0     96      0      0      C
05     96      0      0      0      A
06      9     11      0     76      T
Binding TFs: 1puf_B (Homeobox domain, Homeobox KN domain)
Binding Sites: 1puf_D
1puf_E
			
Publications: LaRonde-LeBlanc N.A, Wolberger C. Structure of HoxA9 and Pbx1 bound to DNA: Hox hexapeptide and DNA recognition anterior to posterior. Genes & development 17:2060-72 (2003). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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