DNA Binding Motif

Accessions: UP00099A_2 (UniPROBE 20160601)
Names: 2410083I15Rik, achaete-scute complex homolog-like 2 (Drosophila), Achaete-scute homolog 2, Ascl2, Mash-2, Mash2
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 16
Consensus: bymwcCCcryccyrty
Weblogo:
PSSM: P0 A C G T
01 0.11 0.35 0.29 0.25 b
02 0.19 0.25 0.12 0.44 y
03 0.34 0.30 0.20 0.16 m
04 0.31 0.12 0.16 0.41 w
05 0.14 0.60 0.12 0.13 c
06 0.08 0.72 0.14 0.07 C
07 0.15 0.69 0.07 0.10 C
08 0.14 0.65 0.13 0.09 c
09 0.34 0.09 0.37 0.20 r
10 0.03 0.63 0.07 0.26 y
11 0.12 0.62 0.10 0.16 c
12 0.11 0.63 0.09 0.17 c
13 0.20 0.25 0.22 0.33 y
14 0.42 0.12 0.28 0.18 r
15 0.11 0.22 0.25 0.43 t
16 0.19 0.30 0.15 0.36 y
Binding TFs: UP00099A (Helix-loop-helix DNA-binding domain)
Binding Sites: AACAGCTG
AACAGGTG
ACACCTGC
ACAGCTGC
ACAGCTGG
ACAGCTGT
ACAGGTGC
AGCAGCTG
AGCAGGTG
CACCTGCA
CACCTGCC
CAGCTGCA
CAGCTGCC
CAGCTGCG
CAGCTGTA
CAGCTGTC
CCACCTGC
CCAGCTGC
GCACCTGC
GCAGCTGC
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]

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