DNA Binding Motif
| Accessions: | HNF1B_full_1 (HumanTF 1.0), MA0153.2 (JASPAR 2024) |
| Names: | HNF1B |
| Organisms: | Homo sapiens, Mus musculus |
| Libraries: | HumanTF 1.0 1, JASPAR 2024 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Notes: | Site type: dimeric; SELEX cycle: 2, HT-SELEX |
| Length: | 13 |
| Consensus: | GTTAATsATTAAy |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 1528 1030 30839 1628 G 02 541 2552 1434 30839 T 03 5730 3466 778 30839 T 04 30839 13 398 49 A 05 30839 1163 140 612 A 06 1944 809 66 30839 T 07 6502 9236 9626 5474 s 08 30839 73 600 1047 A 09 1323 416 1589 30839 T 10 80 665 1 30839 T 11 30839 794 5271 3119 A 12 30839 1472 1980 406 A 13 1790 17114 725 13724 y |
| Type: | Heterodimer |
| Binding TFs: | P35680 (Homeobox domain, Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus, Hepatocyte nuclear factor 1 (HNF-1), N terminus) HNF1B_full (Homeobox domain, Hepatocyte nuclear factor 1 (HNF-1), beta isoform C terminus, Hepatocyte nuclear factor 1 (HNF-1), N terminus) P35680 |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed] |
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