DNA Binding Motif

Accessions: 2nll_AB (3D-footprint 20210203)
Names: PROTEIN (RETINOIC ACID RECEPTOR)
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: RETINOID X RECEPTOR-THYROID HORMONE RECEPTOR DNA-BINDING DOMAIN HETERODIMER BOUND TO THYROID RESPONSE ELEMENT DNA
Length: 15
Consensus: GGtnAnnnnaGGTCA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 0 80 16 G
03 5 21 10 60 t
04 24 24 24 24 n
05 96 0 0 0 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 64 10 10 12 a
11 0 0 96 0 G
12 0 0 96 0 G
13 0 6 5 85 T
14 0 96 0 0 C
15 76 5 10 5 A
Type: Heterodimer
Binding TFs: 2nll_A (Zinc finger, C4 type (two domains))
2nll_B (Zinc finger, C4 type (two domains))
Binding Sites: 2nll_D
2nll_C
Publications: Rastinejad F., Perlmann T., Evans R. M., Sigler P. B. Structural determinants of nuclear receptor assembly on DNA direct repeats. Nature 375:203-211 (1995). [Pubmed]

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