DNA Binding Motif

						

			
Accessions: 6l6q_AB (3D-footprint 20231221)

			
Names: Nuclear receptor related 1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Structural basis of NR4A2 homodimers binding to selective Nur-responsive elements
Length: 16
Consensus: TnACcTnTAnAGGTCA
Weblogo: 
PSSM: P0      A      C      G      T
01      6      5      5     80      T
02     24     24     24     24      n
03     81      5      5      5      A
04      0     96      0      0      C
05     10     64     12     10      c
06     12      5     10     69      T
07     24     24     24     24      n
08      0      0      0     96      T
09     80      5      5      6      A
10     24     24     24     24      n
11     96      0      0      0      A
12      0      0     96      0      G
13      0      0     96      0      G
14      0      0      0     96      T
15      0     96      0      0      C
16     96      0      0      0      A
Binding TFs: 6l6q_A / 6l6q_B (Zinc finger, C4 type (two domains))
Binding Sites: 6l6q_C / 6l6q_F
			
Publications: Jiang L, Dai S, Li J, Liang X, Qu L, Chen X, Guo M, Chen Z, Chen L, Wei H, Chen Y. Structural basis of binding of homodimers of the nuclear receptor NR4A2 to selective Nur-responsive DNA elements. J Biol Chem 294:19795-19803 (2019). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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