DNA Binding Motif

Accessions: 5nm9_A (3D-footprint 20231221)
Names: Mothers against decapentaplegic homolog
Organisms: Trichoplax adhaerens, Trichoplax reptans
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of the placozoa Trichoplax adhaerens Smad4-MH1 bound to the GGCGC site.
Length: 6
Consensus: sCGcCC
Weblogo:
PSSM: P0 A C G T
01 14 24 44 14 s
02 0 96 0 0 C
03 0 0 96 0 G
04 17 51 14 14 c
05 0 96 0 0 C
06 2 66 14 14 C
Binding TFs: 5nm9_A (MH1 domain)
Binding Sites: 5nm9_C / 5nm9_D
Publications: Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun 8:2070 (2017). [Pubmed]

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