DNA Binding Motif

Accessions: 1pzu_B (3D-footprint 20231221)
Names: Nuclear factor of activated T-cells, cytoplasmic 2
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site
Length: 5
Consensus: tGGAa
Weblogo:
PSSM: P0 A C G T
01 13 13 13 57 t
02 0 0 96 0 G
03 0 0 96 0 G
04 96 0 0 0 A
05 54 13 13 16 a
Binding TFs: 1pzu_B (Rel homology domain (RHD), IPT/TIG domain)
Binding Sites: 1pzu_T
1pzu_W
1pzu_X
1pzu_Y
Publications: Jin L, Sliz P, Chen L, Macián F, Rao A, Hogan P.G, Harrison S.C. An asymmetric NFAT1 dimer on a pseudo-palindromic kappa B-like DNA site. Nature structural biology 10:807-11 (2003). [Pubmed]

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