DNA Binding Motif

						

			
Accessions: ELF5_full (HumanTF 1.0), MA0136.2 (JASPAR 2024)

			
Names: ELF5
Organisms: Homo sapiens, Mus musculus
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 2, HT-SELEX
Length: 11
Consensus: acsmGGAAGtr
Weblogo: 
PSSM: P0      A      C      G      T
01   2416    252    301    793      a
02   1221   2298    955    866      c
03    987   2453   1266     97      s
04   1458   2528    309     56      m
05      3      0   3307     20      G
06      5      0   3315     25      G
07   2699     11      1      4      A
08   2646     61      0    245      A
09    890    155   2857     84      G
10    477    716    312   2470      t
11    959    371    762    663      r
Type: Heterodimer
Binding TFs: ELF5_full (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9UKW6 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
Q9UKW6
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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