DNA Binding Motif

Accessions: PerR (DBTBS 1.0)
Names: PerR
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 15
Consensus: TTrkAATkATTATAA
Weblogo:
PSSM: P0 A C G T
01 0 0.18 0 0.82 T
02 0 0 0.18 0.82 T
03 0.65 0 0.35 0 r
04 0 0 0.35 0.65 k
05 1 0 0 0 A
06 1 0 0 0 A
07 0 0 0 1 T
08 0 0 0.47 0.53 k
09 0.78 0 0 0.22 A
10 0 0 0 1 T
11 0 0 0 1 T
12 1 0 0 0 A
13 0 0 0 1 T
14 0.73 0.18 0 0.08 A
15 0.82 0 0.18 0 A
Binding TFs: PerR (Ferric uptake regulator family)
Binding Sites: ahpC_1
fur_1
hemA_1
hemA_2
katA
mrgA_1
perR_1
perR_2
srfAA_4
yjbD_1
ykvW_1
Publications: Herbig A.F, Helmann J.D. Roles of metal ions and hydrogen peroxide in modulating the interaction of the Bacillus subtilis PerR peroxide regulon repressor with operator DNA. Molecular microbiology 41:849-59 (2001). [Pubmed]

Fuangthong M, Herbig A.F, Bsat N, Helmann J.D. Regulation of the Bacillus subtilis fur and perR genes by PerR: not all members of the PerR regulon are peroxide inducible. Journal of bacteriology 184:3276-86 (2002). [Pubmed]

Engelmann S, Lindner C, Hecker M. Cloning, nucleotide sequence, and regulation of katE encoding a sigma B-dependent catalase in Bacillus subtilis. Journal of bacteriology 177:5598-605 (1995). [Pubmed]

Bol D.K, Yasbin R.E. Analysis of the dual regulatory mechanisms controlling expression of the vegetative catalase gene of Bacillus subtilis. Journal of bacteriology 176:6744-8 (1994). [Pubmed]

Hayashi K, Ohsawa T, Kobayashi K, Ogasawara N, Ogura M. The H2O2 stress-responsive regulator PerR positively regulates srfA expression in Bacillus subtilis. Journal of bacteriology 187:6659-67 (2005). [Pubmed]

Gaballa A, Wang T, Ye R.W, Helmann J.D. Functional analysis of the Bacillus subtilis Zur regulon. Journal of bacteriology 184:6508-14 (2002). [Pubmed]

Leelakriangsak M, Kobayashi K, Zuber P. Dual negative control of spx transcription initiation from the P3 promoter by repressors PerR and YodB in Bacillus subtilis. Journal of bacteriology 189:1736-44 (2007). [Pubmed]

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