DNA Binding Motif

Accessions: 2wbu_A (3D-footprint 20231221)
Names: KRUEPPEL-LIKE FACTOR 4
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: CRYSTAL STRUCTURE OF THE ZINC FINGER DOMAIN OF KLF4 BOUND TO ITS TARGET DNA
Length: 10
Consensus: GGGGCGTGGc
Weblogo:
PSSM: P0 A C G T
01 9 9 69 9 G
02 19 1 76 0 G
03 0 0 96 0 G
04 0 0 96 0 G
05 0 96 0 0 C
06 0 0 96 0 G
07 9 1 0 86 T
08 0 0 96 0 G
09 0 0 96 0 G
10 9 59 9 19 c
Binding TFs: 2wbu_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Sites: 2wbu_B
2wbu_C
Publications: Schuetz A, Nana D, Rose C, Zocher G, Milanovic M, Koenigsmann J, Blasig R, Heinemann U, Carstanjen D. The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation. Cellular and molecular life sciences : CMLS 68:3121-31 (2011). [Pubmed]

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