DNA Binding Motif

						

			
Accessions: TFAP2C_DBD_3 (HumanTF 1.0), MA0815.1 (JASPAR 2024)

			
Names: TFAP2C, TFAP2C(var.3)
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 13
Consensus: tGCCCysrGGGCa
Weblogo: 
PSSM: P0      A      C      G      T
01    532    350    215   1466      t
02      0    659   2379      0      G
03      0   2496      0      0      C
04      0   2408      0      0      C
05     17   2073     95    330      C
06     89   1001    404   1217      y
07    365    913    924    425      s
08   1013    362    984     73      r
09    380    110   2359     20      G
10      0      0   3082      0      G
11      0      0   3137      0      G
12      0   2128    519      0      C
13   1282    174    343    435      a
Type: Heterodimer
Binding TFs: Q92754 (Transcription factor AP-2)
TFAP2C_DBD (Transcription factor AP-2)
Q92754
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Eckert D, Buhl S, Weber S, Jäger R, Schorle H. The AP-2 family of transcription factors. Genome Biol : (2005;6(13):246.). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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