DNA Binding Motif

Accessions: FOXC2_DBD_3 (HumanTF 1.0), MA0846.1 (JASPAR 2024)
Names: FOXC2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 12
Consensus: wAwrTAAAYAww
Weblogo:
PSSM: P0 A C G T
01 8939 1279 454 11517 w
02 20456 1652 5093 2080 A
03 11301 3476 3129 9155 w
04 6418 440 14038 136 r
05 2005 3773 321 20456 T
06 20456 6759 87 122 A
07 20456 344 81 107 A
08 20456 105 279 242 A
09 31 14435 68 6021 Y
10 20456 101 328 215 A
11 13296 2087 1710 7160 w
12 10995 3080 2649 9461 w
Type: Heterodimer
Binding TFs: FOXC2_DBD (Fork head domain)
Q99958 (Fork head domain)
Q99958
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Weirauch MT, Cote A, Norel R, Annala M, Zhao Y, Riley TR, Saez-Rodriguez J, Cokelaer T, Vedenko A, Talukder S; DREAM5 Consortium, Bussemaker HJ, Morris QD, Bulyk ML, Stolovitzky G, Hughes TR. Evaluation of methods for modeling transcription factor sequence specificity. Nat Biotechnol 31:126-34 (2013). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.