DNA Binding Motif

						

			
Accessions: ATF6_4 (HT-SELEX2 May2017), MA1466.1 (JASPAR 2024)

			
Names: ATF6
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1, JASPAR 2024 2
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: HT-SELEX
Length: 14
Consensus: tgrTGACGTGGCAs
Weblogo: 
PSSM: P0      A      C      G      T
01     87    234    114    723      t
02    148    234   1158    277      g
03    743    192    415      4      r
04      0      2      0   1158      T
05      3      3   1158      4      G
06   1158      1     11      2      A
07      0   1158      0      1      C
08      2      0   1158      0      G
09      0      3      0   1158      T
10     25      0   1158     15      G
11      7      1   1158    196      G
12     30   1158      0     12      C
13   1158     56    274     57      A
14    240    301    346    271      s
Type: Heterodimer
Binding TFs: P18850 (bZIP transcription factor, Basic region leucine zipper)
ATF6 (bZIP transcription factor, Basic region leucine zipper)
P18850
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Wang Y., Shen J., Arenzana N., Tirasophon W., Kaufman R. J., Prywes R. Activation of ATF6 and an ATF6 DNA binding site by the endoplasmic reticulum stress response.. J. Biol. Chem. 275:27013-27020 (2000). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.