DNA Binding Motif

Accessions: 3l1p_AB (3D-footprint 20231221)
Names: POU domain, class 5, transcription factor 1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: POU protein:DNA complex
Length: 17
Consensus: CATTTGCCTTTCAAATG
Weblogo:
PSSM: P0 A C G T
01 0 88 4 4 C
02 96 0 0 0 A
03 0 0 0 96 T
04 4 4 4 84 T
05 0 0 0 96 T
06 0 0 96 0 G
07 4 88 0 4 C
08 4 80 4 8 C
09 0 0 0 96 T
10 0 0 0 96 T
11 4 4 4 84 T
12 0 88 8 0 C
13 96 0 0 0 A
14 84 4 4 4 A
15 96 0 0 0 A
16 4 4 0 88 T
17 4 4 84 4 G
Type: Heterodimer
Binding TFs: 3l1p_A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
3l1p_B (Homeobox domain, Pou domain - N-terminal to homeobox domain)
Binding Sites: 3l1p_M
3l1p_N
Publications: Esch D, Vahokoski J, Groves M.R, Pogenberg V, Cojocaru V, Vom Bruch H, Han D, Drexler H.C, Araúzo-Bravo M.J, Ng C.K, Jauch R, Wilmanns M, Schöler H.R. A unique Oct4 interface is crucial for reprogramming to pluripotency. Nature cell biology 15:295-301 (2013). [Pubmed]

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