DNA Binding Motif

Accessions: EVX1_DBD (HumanTF 1.0), MA0887.1 (JASPAR 2018)
Names: EVX1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2018 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Khan A, Fornes O, Stigliani A, Gheorghe M, Castro-Mondragon JA, van der Lee R, Bessy A, Cheneby , Kulkarni SR, Tan G, Baranasic D, Arenillas DJ, Sandelin A, Vandepoele K, Lenhard B, Ballester B, Wasserman WW, Parcy F, Mathelier A (2017) JASPAR 2018: update of the open-access database of transcription factor binding profiles and its web framework. Nucleic Acids Res. doi: 10.1093/nar/gkx1126 [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 3, HT-SELEX
Length: 10
Consensus: gvtaATTAsc
Weblogo:
PSSM: P0 A C G T
01 1959 1806 3092 1037 g
02 2045 2506 2629 714 v
03 1196 2343 269 7894 t
04 3899 1752 1885 358 a
05 7894 29 236 0 A
06 0 67 267 7894 T
07 232 463 171 7894 T
08 7894 14 725 172 A
09 1333 2098 2720 1743 s
10 1432 3318 1958 1186 c
Type: Heterodimer
Binding TFs: P49640 (Homeobox domain)
EVX1_DBD (Homeobox domain)
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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