DNA Binding Motif

						

			
Accessions: POU3F3_DBD_1 (HumanTF 1.0), MA0788.1 (JASPAR 2024)

			
Names: POU3F3
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: monomeric; SELEX cycle: 4, HT-SELEX
Length: 13
Consensus: wwTATGCwAATtw
Weblogo: 
PSSM: P0      A      C      G      T
01    576     75    137    290      w
02    440     41    131    637      w
03    129     57     64   1078      T
04   1078     11     12     30      A
05     25     33     49   1078      T
06     22     10   1078     86      G
07     28   1078    118    343      C
08    506      4      1    572      w
09   1078     11     77     79      A
10   1078      6     15     14      A
11     53     20     12   1078      T
12    240    141    237   1078      t
13    536     85    115    542      w
Type: Heterodimer
Binding TFs: P20264 (Homeobox domain, Pou domain - N-terminal to homeobox domain)
POU3F3_DBD (Homeobox domain, Pou domain - N-terminal to homeobox domain)
P20264
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Rhee J. M., Gruber C. A., Brodie T. B., Trieu M., Turner E. E. Highly cooperative homodimerization is a conserved property of neural POU proteins. J. Biol. Chem. 273:34196-34205 (1998). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
Disclaimer and license


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.