DNA Binding Motif

Accessions: 6gat_A (3D-footprint 20231221)
Names: NITROGEN REGULATORY PROTEIN AREA
Organisms: Emericella nidulans, Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: SOLUTION NMR STRUCTURE OF THE L22V MUTANT DNA BINDING DOMAIN OF AREA COMPLEXED TO A 13 BP DNA CONTAINING A TGATA SITE, REGULARIZED MEAN STRUCTURE
Length: 6
Consensus: TGATnG
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 0 0 96 0 G
03 67 9 11 9 A
04 11 9 9 67 T
05 24 24 24 24 n
06 9 11 67 9 G
Binding TFs: 6gat_A (GATA zinc finger)
Binding Sites: 6gat_B
6gat_C
Publications: Starich M.R, Wikström M, Schumacher S, Arst H.N, Gronenborn A.M, Clore G.M. The solution structure of the Leu22-->Val mutant AREA DNA binding domain complexed with a TGATAG core element defines a role for hydrophobic packing in the determination of specificity. Journal of molecular biology 277:621-34 (1998). [Pubmed]

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