DNA Binding Motif

						

			
Accessions: CREB3L1_DBD_1 (HumanTF 1.0), MA0839.1 (JASPAR 2024)

			
Names: CREB3L1
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 4, HT-SELEX
Length: 14
Consensus: rTGCCACGTCAyCa
Weblogo: 
PSSM: P0      A      C      G      T
01    247    143    181    100      r
02     38    159     29    671      T
03     20      3    671     18      G
04     61    671      0      2      C
05      3    671      0      5      C
06    671      0      3      0      A
07      0    671      3      0      C
08     21      3    671      0      G
09      7      0      3    671      T
10    121    671     40     10      C
11    671     33     72     39      A
12     60    186    125    300      y
13     76    671     64     79      C
14    671     65    167    127      a
Type: Heterodimer
Binding TFs: CREB3L1_DBD (bZIP transcription factor, Basic region leucine zipper)
Q96BA8 (bZIP transcription factor, Basic region leucine zipper)
Q96BA8
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]


Fox RM, Hanlon CD, Andrew DJ. The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity. J Cell Biol 191:479-92 (2010). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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