DNA Binding Motif

Accessions: 4cn2_CD (3D-footprint 20231221)
Names: RETINOIC ACID RECEPTOR RXR-ALPHA
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Ramp2 Response Element
Length: 12
Consensus: GGTCAngGGTCA
Weblogo:
PSSM: P0 A C G T
01 0 0 96 0 G
02 0 1 76 19 G
03 9 14 4 69 T
04 0 96 0 0 C
05 72 9 4 11 A
06 24 24 24 24 n
07 14 9 64 9 g
08 0 0 96 0 G
09 0 0 96 0 G
10 1 4 0 91 T
11 0 96 0 0 C
12 76 12 4 4 A
Type: Heterodimer
Binding TFs: 4cn2_C (Zinc finger, C4 type (two domains))
4cn2_D (Zinc finger, C4 type (two domains))
Binding Sites: 4cn2_A
4cn2_B
Publications: Osz J, McEwen A.G, Poussin-Courmontagne P, Moutier E, Birck C, Davidson I, Moras D, Rochel N. Structural basis of natural promoter recognition by the retinoid X nuclear receptor. Scientific reports 5:8216 (2015). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.