DNA Binding Motif

						

			
Accessions: UP00187A_1 (UniPROBE 20160601)

			
Names: ALX-4, Alx4, aristaless 4, Aristaless-like 4, Homeobox protein aristaless-like 4
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 17
Consensus: cgcryTAATTArthasc
Weblogo: 
PSSM: P0      A      C      G      T
01   0.16   0.59   0.15   0.11      c
02   0.10   0.24   0.56   0.10      g
03   0.19   0.44   0.16   0.21      c
04   0.40   0.15   0.29   0.16      r
05   0.02   0.34   0.01   0.62      y
06   0.01   0.08      0   0.92      T
07   0.99   0.01   0.01      0      A
08   0.98      0   0.01   0.01      A
09   0.01   0.01      0   0.98      T
10      0   0.01   0.01   0.99      T
11   0.92      0   0.08   0.01      A
12   0.62   0.01   0.34   0.02      r
13   0.17   0.23   0.18   0.42      t
14   0.29   0.28   0.13   0.30      h
15   0.36   0.23   0.19   0.22      a
16   0.23   0.29   0.25   0.23      s
17   0.12   0.43   0.21   0.24      c
Binding TFs: UP00187A (Homeobox domain)
Binding Sites: AATAATTA
AATTAATT
ACCAATTA
ACTAATTA
ATAATTAA
ATAATTAG
ATTAATTA
CAATTAAG
CCAATTAA
CCAATTAG
CCTAATTA
CTAATTAA
CTAATTAG
CTTAATTA
GCCAATTA
GCTAATTA
GTAATTAA
GTTAATTA
TAATTAAA
TAATTAGA
			
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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