DNA Binding Motif

Accessions: 5mhk_CDJ (3D-footprint 20231221)
Names: RS1
Organisms: Human herpes simplex virus 1, Human herpesvirus 1 (strain 17) (HHV-1)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: ICP4 DNA-binding domain in complex with 19mer DNA duplex from its own promoter
Length: 12
Consensus: CGnnnnnaCGAT
Weblogo:
PSSM: P0 A C G T
01 0 96 0 0 C
02 0 0 96 0 G
03 24 24 24 24 n
04 24 24 24 24 n
05 24 24 24 24 n
06 24 24 24 24 n
07 24 24 24 24 n
08 48 16 16 16 a
09 0 96 0 0 C
10 0 0 96 0 G
11 80 0 16 0 A
12 0 16 0 80 T
Type: Heterodimer
Binding TFs: 5mhk_C (Herpesvirus ICP4-like protein N-terminal region)
5mhk_D (Herpesvirus ICP4-like protein N-terminal region)
Publications: Tunnicliffe RB, Lockhart-Cairns MP, Levy C, Mould AP, Jowitt TA, Sito H, Baldock C, Sandri-Goldin RM, Golovanov AP. The herpes viral transcription factor ICP4 forms a novel DNA recognition complex. Nucleic Acids Res 45:8064-8078 (2017). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.