DNA Binding Motif

Accessions: NFKB2_DBD (HumanTF 1.0), MA0778.1 (JASPAR 2024)
Names: NFKB2
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1, JASPAR 2024 2
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: Site type: dimeric; SELEX cycle: 3, HT-SELEX
Length: 13
Consensus: aGGGGAwTCCCCy
Weblogo:
PSSM: P0 A C G T
01 5041 2456 2306 1980 a
02 101 97 16291 4 G
03 1 1 16041 3 G
04 8 5 16055 565 G
05 2663 11 13129 987 G
06 8380 977 856 636 A
07 5182 60 51 5970 w
08 1173 1395 1077 10976 T
09 852 11011 19 1867 C
10 256 12673 1 44 C
11 2 12710 1 2 C
12 8 12888 3 23 C
13 1527 3324 2182 5985 y
Type: Heterodimer
Binding TFs: Q00653 (Ankyrin repeat, Death domain, Rel homology domain (RHD), Ankyrin repeats (3 copies), Ankyrin repeat, Ankyrin repeats (many copies), Ankyrin repeats (many copies))
NFKB2_DBD (Rel homology domain (RHD))
Q00653
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]

Wan F, Lenardo MJ. Specification of DNA binding activity of NF-kappaB proteins. Cold Spring Harb Perspect Biol : (2009). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.