DNA Binding Motif

Accessions: 3ikt_AB (3D-footprint 20231221)
Names: Redox-sensing transcriptional repressor rex
Organisms: strain HB27 / ATCC BAA-163 / DSM 7039, Thermus thermophilus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal structure of a Rex-family repressor/DNA/NAD+ complex from Thermus aquaticus
Length: 18
Consensus: TGTGAnnnnnnTCACAGC
Weblogo:
PSSM: P0 A C G T
01 6 3 3 84 T
02 0 0 96 0 G
03 6 3 3 84 T
04 0 0 96 0 G
05 87 3 3 3 A
06 24 24 24 24 n
07 24 24 24 24 n
08 24 24 24 24 n
09 24 24 24 24 n
10 24 24 24 24 n
11 24 24 24 24 n
12 3 7 3 83 T
13 0 96 0 0 C
14 96 0 0 0 A
15 0 96 0 0 C
16 84 6 3 3 A
17 3 3 81 9 G
18 8 70 11 7 C
Type: Heterodimer
Binding TFs: 3ikt_A (CoA binding domain, Putative DNA-binding protein N-terminus)
3ikt_B (CoA binding domain, Putative DNA-binding protein N-terminus)
Binding Sites: 3ikt_C / 3ikt_D
Publications: McLaughlin K.J, Strain-Damerell C.M, Xie K, Brekasis D, Soares A.S, Paget M.S, Kielkopf C.L. Structural basis for NADH/NAD+ redox sensing by a Rex family repressor. Molecular cell 38:563-75 (2010). [Pubmed]

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