DNA Binding Motif

Accessions: 5cbx_E (3D-footprint 20210203)
Names: AncGR DNA Binding Domain
Organisms: Homo sapiens
Libraries: 3D-footprint 20210203 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: AncGR DNA Binding Domain - (+)GRE Complex
Length: 5
Consensus: gnaCA
01 16 13 54 13 g
02 24 24 24 24 n
03 54 13 16 13 a
04 0 96 0 0 C
05 96 0 0 0 A
Binding TFs: 5cbx_E (Zinc finger, C4 type (two domains))
Binding Sites: 5cbx_H
Publications: Hudson WH, Kossmann BR, de Vera IM, Chuo SW, Weikum ER, Eick GN, Thornton JW, Ivanov IN, Kojetin DJ, Ortlund EA. Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space. Proc Natl Acad Sci U S A 113:326-31 (2016). [Pubmed]


These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research.