DNA Binding Motif

						

			
Accessions: 1lei_AB (3D-footprint 20231221)

			
Names: NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: The kB DNA sequence from the HLV-LTR functions as an allosteric regulator of HIV transcription
Length: 12
Consensus: TGGGnnngTACA
Weblogo: 
PSSM: P0      A      C      G      T
01      6      6      1     83      T
02      0      0     96      0      G
03      0      0     83     13      G
04      0      0     96      0      G
05     24     24     24     24      n
06     24     24     24     24      n
07     24     24     24     24      n
08     12      0     64     20      g
09      0      0      0     96      T
10     66     12      6     12      A
11      0     96      0      0      C
12     76      8      6      6      A
Type: Heterodimer
Binding TFs: 1lei_A (Rel homology domain (RHD))
1lei_B (Rel homology domain (RHD))
Binding Sites: 1lei_C
1lei_D
			
Publications: Chen-Park F.E, Huang D.B, Noro B, Thanos D, Ghosh G. The kappa B DNA sequence from the HIV long terminal repeat functions as an allosteric regulator of HIV transcription. The Journal of biological chemistry 277:24701-8 (2002). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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