DNA Binding Motif

Accessions: MA0597.1 (JASPAR 2024)
Names: THAP1
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Notes: ChIP-seq
Length: 9
Consensus: ytGCCMkya
Weblogo:
PSSM: P0 A C G T
01 18 93 27 61 y
02 15 47 12 125 t
03 20 0 137 42 G
04 7 182 0 10 C
05 3 195 0 1 C
06 58 136 1 4 M
07 47 17 77 58 k
08 30 71 41 57 y
09 116 34 17 32 a
Type: Heterodimer
Binding TFs: Q9NVV9 (THAP domain)
Q9NVV9
Binding Sites: MA0597.1.1
MA0597.1.10
MA0597.1.11
MA0597.1.12
MA0597.1.13
MA0597.1.14
MA0597.1.15
MA0597.1.16
MA0597.1.17
MA0597.1.18
MA0597.1.19
MA0597.1.2
MA0597.1.20
MA0597.1.3
MA0597.1.4
MA0597.1.5
MA0597.1.6
MA0597.1.7
MA0597.1.8
MA0597.1.9
Publications: Clouaire T, Roussigne M, Ecochard V, Mathe C, Amalric F, Girard J.P. The THAP domain of THAP1 is a large C2CH module with zinc-dependent sequence-specific DNA-binding activity. Proceedings of the National Academy of Sciences of the United States of America 102:6907-12 (2005). [Pubmed]

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