DNA Binding Motif

Accessions: 1c7u_B (3D-footprint 2022-04-03)
Names: MYOCYTE-SPECIFIC ENHANCER FACTOR 2A, C4 FORM
Organisms: Homo sapiens
Libraries: 3D-footprint 2022-04-03 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Complex of the DNA binding core domain of the transcription factor MEF2A with a 20mer oligonucleotide
Length: 6
Consensus: TAgncG
Weblogo:
PSSM: P0 A C G T
01 0 0 0 96 T
02 96 0 0 0 A
03 16 13 54 13 g
04 24 24 24 24 n
05 13 57 13 13 c
06 0 0 96 0 G
Binding TFs: 1c7u_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Sites: 1c7u_C / 1c7u_D
Publications: Huang K, Louis J.M, Donaldson L, Lim F.L, Sharrocks A.D, Clore G.M. Solution structure of the MEF2A-DNA complex: structural basis for the modulation of DNA bending and specificity by MADS-box transcription factors. The EMBO journal 19:2615-28 (2000). [Pubmed]

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