DNA Binding Motif

						

			
Accessions: CUX1_FOXO1 (HumanTF2 1.0)

			
Names: CUX1_FOXO1
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 19
Consensus: rtAAayAaaatgATCrATa
Weblogo: 
PSSM: P0      A      C      G      T
01    132     81    227     18      r
02     95     62     33    227      t
03    175     52     11     10      A
04    227     23      1     13      A
05    227     10     45     92      a
06     10    227      4    116      y
07    227     21     15     18      A
08    150     31     34     11      a
09    109     24     38     55      a
10    115     51     21     40      a
11     45     27     51    104      t
12     52     10    114     51      g
13    227      1     10      1      A
14      1      1      6    227      T
15      7    227      0     15      C
16    108     10    119      6      r
17    227      0      0      9      A
18     25      0      0    227      T
19     78     51     50     48      a
Type: Heterodimer
Binding TFs: CUX1_TF1 (Homeobox domain, CUT domain, Homeobox KN domain)
FOXO1_TF1 / FOXO1_TF2 (Fork head domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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