DNA Binding Motif

						

			
Accessions: 4iri_A (3D-footprint 20231221)

			
Names: Transcriptional regulator ERG
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Auto-inhibited ERG Ets Domain-DNA Complex
Length: 6
Consensus: CGGAag
Weblogo: 
PSSM: P0      A      C      G      T
01      0     96      0      0      C
02      0      0     96      0      G
03      0      0     96      0      G
04     96      0      0      0      A
05     57     13     13     13      a
06     13     13     54     16      g
Binding TFs: 4iri_A (Ets-domain)
Binding Sites: 4iri_B
4iri_C
			
Publications: Regan M.C, Horanyi P.S, Pryor E.E, Sarver J.L, Cafiso D.S, Bushweller J.H. Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited. Proceedings of the National Academy of Sciences of the United States of America 110:13374-9 (2013). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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