DNA Binding Motif
| Accessions: | 1by4_B (3D-footprint 20231221), 1dsz_A (3D-footprint 20231221) |
| Names: | PROTEIN (RETINOIC ACID RECEPTOR RXR-ALPHA), RETINOIC ACID RECEPTOR ALPHA |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | STRUCTURE AND MECHANISM OF THE HOMODIMERIC ASSEMBLY OF THE RXR ON DNA, STRUCTURE OF THE RXR/RAR DNA-BINDING DOMAIN HETERODIMER IN COMPLEX WITH THE RETINOIC ACID RESPONSE ELEMENT DR1 |
| Length: | 5 |
| Consensus: | tGaCC |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 13 16 13 54 t 02 0 0 96 0 G 03 54 13 13 16 a 04 0 96 0 0 C 05 0 96 0 0 C |
| Type: | Heterodimer |
| Binding TFs: | 1by4_B (Zinc finger, C4 type (two domains)) 1dsz_A (Zinc finger, C4 type (two domains)) |
| Binding Sites: | 1dsz_C 1dsz_D 1by4_E / 1by4_G 1by4_F / 1by4_H |
| Publications: | Zhao Q, Chasse S.A, Devarakonda S, Sierk M.L, Ahvazi B, Rastinejad F. Structural basis of RXR-DNA interactions. Journal of molecular biology 296:509-20 (2000). [Pubmed] Rastinejad F., Wagner T., Zhao Q., Khorasanizadeh S. Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.. EMBO J. 19:1045-1054 (2000). [Pubmed] |
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