DNA Binding Motif

Accessions: 2ql2_CD (3D-footprint 20231221)
Names: Transcription factor E2-alpha
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Crystal Structure of the basic-helix-loop-helix domains of the heterodimer E47/NeuroD1 bound to DNA
Length: 8
Consensus: CCAGntGG
Weblogo:
PSSM: P0 A C G T
01 0 82 7 7 C
02 0 96 0 0 C
03 96 0 0 0 A
04 14 0 68 14 G
05 24 24 24 24 n
06 7 14 16 59 t
07 0 0 96 0 G
08 7 7 73 9 G
Type: Heterodimer
Binding TFs: 2ql2_C (Helix-loop-helix DNA-binding domain)
2ql2_D (Helix-loop-helix DNA-binding domain)
Binding Sites: 2ql2_G
2ql2_H
Publications: Longo A, Guanga G.P, Rose R.B. Crystal structure of E47-NeuroD1/beta2 bHLH domain-DNA complex: heterodimer selectivity and DNA recognition. Biochemistry 47:218-29 (2008). [Pubmed]

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