DNA Binding Motif

Accessions: 5eh2_F (3D-footprint 20231221)
Names: Histone-lysine N-methyltransferase PRDM9
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Human PRDM9 allele-A ZnF Domain with Associated Recombination Hotspot DNA Sequence III
Length: 12
Consensus: mCTCCCTAGCCa
Weblogo:
PSSM: P0 A C G T
01 31 39 13 13 m
02 1 92 2 1 C
03 3 3 3 87 T
04 4 82 5 5 C
05 1 95 0 0 C
06 2 90 2 2 C
07 0 3 1 92 T
08 71 1 22 2 A
09 3 0 93 0 G
10 12 74 5 5 C
11 0 95 1 0 C
12 57 13 13 13 a
Binding TFs: 5eh2_F (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Sites: 5eh2_C
5eh2_D
Publications: Patel A, Horton JR, Wilson GG, Zhang X, Cheng X. Structural basis for human PRDM9 action at recombination hot spots. Genes Dev 30:257-65 (2016). [Pubmed]

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