DNA Binding Motif

Accessions: 4xrs_BI (3D-footprint 20231221)
Names: Homeobox protein Meis1
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: Heterodimeric complex of transcription factors MEIS1 and DLX3 on specific DNA
Length: 9
Consensus: ganmngatA
Weblogo:
PSSM: P0 A C G T
01 13 13 56 14 g
02 38 19 20 19 a
03 24 24 24 24 n
04 27 25 22 22 m
05 24 24 24 24 n
06 21 21 31 23 g
07 60 12 12 12 a
08 10 13 10 63 t
09 96 0 0 0 A
Type: Heterodimer
Binding TFs: 4xrs_B (Homeobox domain, Homeobox KN domain)
4xrs_I (Homeobox domain)
Binding Sites: 4xrs_D
4xrs_E
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

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