DNA Binding Motif

Accessions: 1ysa_CD (3D-footprint 20231221)
Names: PROTEIN (GCN4)
Organisms: Saccharomyces cerevisiae, Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Description: THE GCN4 BASIC REGION LEUCINE ZIPPER BINDS DNA AS A DIMER OF UNINTERRUPTED ALPHA HELICES: CRYSTAL STRUCTURE OF THE PROTEIN-DNA COMPLEX
Length: 7
Consensus: TGAGTCA
Weblogo:
PSSM: P0 A C G T
01 11 9 9 67 T
02 9 11 67 9 G
03 96 0 0 0 A
04 0 0 96 0 G
05 0 0 0 96 T
06 9 67 9 11 C
07 96 0 0 0 A
Type: Heterodimer
Binding TFs: 1ysa_C (bZIP transcription factor, Basic region leucine zipper)
1ysa_D (bZIP transcription factor, Basic region leucine zipper)
Binding Sites: 1ysa_A
1ysa_B
Publications: Ellenberger T., Brandl C. J., Struhl K., Harrison S. C. The GCN4 basic region leucine zipper binds DNA as a dimer of uninterrupted helices: Crystal structure of the protein-DNA complex. Cell 71:1223-1237 (1992). [Pubmed]

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